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NAV1.2 ALPHA SUBUNIT
Descriptors Found:
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DeCS
Descriptor
English
:
NAV1.2 Voltage-Gated Sodium Channel
Descriptor
Spanish
:
Canal de Sodio Activado por Voltaje NAV1.2
Descriptor
Portuguese
:
Canal de Sódio Disparado por Voltagem NAV1.2
Synonyms
English
:
NAV1.2 Voltage Gated Sodium Channel
NAV1.2 alpha Subunit
SCN2A Sodium Channel alpha Subunit
Sodium Channel Protein Type 2 Subunit alpha
Sodium Channel, Voltage-Gated, Type II, alpha 1
Sodium Channel, Voltage-Gated, Type II, alpha 1 Subunit
Type 2 Voltage Gated Sodium Channel
Type 2 Voltage-Gated Sodium Channel
Voltage Gated Sodium Channel Type 2
Voltage Gated Sodium Channel Type 2 Subunit alpha
Voltage Gated Sodium Channel Type 2 alpha Subunit
Voltage-Gated Sodium Channel Type 2
Voltage-Gated Sodium Channel Type 2 Subunit alpha
Voltage-Gated Sodium Channel Type 2 alpha Subunit
Tree Number:
D12.776.157.530.400.875.750.200
D12.776.543.550.450.875.750.200
D12.776.543.585.400.875.750.200
D12.776.631.960.200
Definition
English
:
A voltage-gated
sodium
channel subtype that mediates the
sodium
ion
permeability
of excitable
membranes
. Defects in the SCN2A gene which codes for the alpha subunit of this
sodium
channel are associated with benign familial infantile
seizures
type 3, and early infantile epileptic encephalopathy type 11.
Entry Combination - descr/qualif
English
:
NAV1.2 Voltage-Gated Sodium Channel
/
antagonists & inhibitors
use
Voltage-Gated Sodium Channel Blockers
NAV1.2 Voltage-Gated Sodium Channel
/
agonists
use
Voltage-Gated Sodium Channel Agonists
History Note
English
:
2013
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54948
Unique Identifier:
D062551
Occurrence in VHL
:
Similar:
DeCS